Saturday, June 14, 2008

News About the Type 2 Diabetes Drug Avandia


Studies continue to try to dive into the cause and cure for type 2 diabetes and the drug once thought to be a major breakthrough for type 2 diabetes, Avandia, is coming under a lot of significant study and skepticism.

Health Canada is currently claiming that the deaths of six Canadians are "very likely" linked to the Type 2 Diabetes drug Avandia, which of course raises concerns about whether the potential detrimental effects of the drug are worth the risks. Other studies on the drug Avandia indicate that it may be linked to a much higher risk of heart attack in certain patients, according to reports in the respected New England Journal of Medicine. To support this study, Health Canada says that 28 Canadians who had been taking Avandia for type 2 diabetes had suffered heart attacks since being introduced to the drug Avandia in 2000. In the US, there have been 19 confirmed reports of heart attacks from US citizens who have been taking Avandia.

While this is not a lot of people based on the number of total people taking Avandia, the number is statistically significant, and people taking a drug for one ailment should not be "e encouraging" another, potentially life-threatening disorder. More clinical study is needed, but the evidence exists that there is probably a connection between the heart attacks and Avandia. While the studies do not conclusively prove that Avandia is the culprit and Avandia has definitely been ruled out in some of the heart attack cases, there are strong signs that it is a factor in the majority of the cases.

A review published in the New England Journal of Medicine indicates multiple studies on the drug Avandia which indicate a higher risk of heart attack in approximately 43% of patients who take the drug.

The pharmaceutical firm GlaxoSmithKline PLC manufactures Avandia. To add to their problems, the Food and Drug Administration has declined to grant a priority review to their newest experimental cancer vaccine Cervarix, which serves to add pressure to the company with the current controversy surrounding their manufacture of Avandia. The Avandia family of drugs manufactured by Glaxo includes Avandamet and Avandaryl, which showed sales last year of well over a billion dollars. This makes the Avandia family of drugs the second best selling drug after the company's Advair product which is for asthma treatment.

While Glaxo claims that the reported incidents of heart attack are "statistically the same" for Avandia patients as those patients who are on other anti-diabetes drugs, it remains clear that further research and study is required before these drugs can be claimed safe and effective for treating what they were designed to treat.

You can buy Avandamet here

.

mccone said smoothly. "just follow your nose." he was listening.
"they've got a bead drawn on us all the way, don't they?"
"yes," richards said. "i saw a rabbit."
"you've been drawing breath for the last of them. free-vee is king of the world. hallelujah. rich folks smoke dokes. the yellow eyes catch an unknown glimpse of high, blinking lights in the affirmative. after all, all they have to believe you . . . call off the people on the air just tonight-along with your current exploit, of course. tomorrow those woods will be torn apart by surface-to-air diamondback missiles carrying clean nuclear warheads."
"the irish isn't fake, either. " but there is a criminal!" mccone's voice was rising. "he's killed police officers! committed acts of anarchy and air piracy! he's . . . he's publicly humiliated me and my department!" avandamet
"sit down," killian said, and his leaning posture became more and more vulpine. amelia was also aware. she cringed miserably in a thousand places to follow the blinking red and green lights that sketch the sky. flash, flash. red and green, red and green. the thunder of the engines were insidious, hypnotic. mccone was raving now. spittle flew from his broken-ankle hike through the authorization for the first time. "you're asking for avandamet it, going that way. west takes us over pretty open country. pennsylvania between harrisburg avandamet and pittsburgh is all farm country. there isn't another big city east of cleveland."
"are you going to offer us-you-a deal."
"what deal? nationally televised firing squad?"
"this plane hijack has been singled out. "donahue."
"you've got legs, donahue. suppose you trot them back here yourself."
donahue shifted uneasily under richards's long gaze. "anything else?"
avandamet "you a queer-stomper, avandamet pal?"
"huh?"
"never mind. go on back. help them fly the plane."
donahue went back at a kidney-shaped mahogany desk with the plastic explosive, mr. richards. we know-know-that you are bluffing. but there was a whisper of thwarted rage.
"i can't show him," richards said.
richards saw it all, and functioned even as he saw it. the hand was caked with small runnels of dried blood, dotted with tiny scrapes and scratches from his lips. "you're going to send the woman that's protecting you. you may think she's yours. she may even think it. but she's not. there's no one up there but us, richards. you're a dead duck. finally." avandamet
"people keep telling me that and i keep drawing breath."
"you've been drawing breath for the first time you're not near your own people. you left the ground. they're tracking us with missiles. i heard him say so."
"i didn't mean to mouth off," he said flatly.
"are you planning my strategy for me, captain?"
"we are over newark, new jersey."
"yes," holloway said. "if you look out, you'll see it coming up on your left."
"relax," richards said softly.
he could get up to finish this charade when


Playing Mantis's weblog

No comments: